Category: Neuropathy

Desensitization for neuropathic pain

Because pain is so deeply wired in the brain as a danger signal, patients with pain often avoid touching or using painful areas. However, stimulation & use actually help some neuropathic pain conditions. “Graded desensitization”, by stimulating nerves just enough to be uncomfortable, resets painful nerves in some pain conditions. Beginner Massages Using body lotion, apply…

Read more Desensitization for neuropathic pain

Gabapentinoids for pain

For chronic pain conditions, gabapentinoids (gabapentin & pregabalin) are often first-line treatments because of their effectiveness & safety. They bind to a2d which alters activity of calcium channels on nerves, thereby modulating pain signals before they reach the brain. Pharmacology of gabapentinoids The absorption of gabapentin & pregabalin differ. Gabapentin absorption is slow. Beyond a…

Read more Gabapentinoids for pain

Treating pain at nerve-body interface

Small sensory nerves throughout the body gather information & interact with the body directly. This nerve-body interface underlies many diseases. In chronic pain, nerves cause “neurogenic inflammation” by activating blood vessels, skin, & immune cells. This is the site of action of many pain treatments. Key nerve-body interfaces Neural-vascular: Sensory nerves open blood vessels. This…

Read more Treating pain at nerve-body interface

Spinal column stimulation (SCS) for the treatment of chronic pain

Spinal column stimulation (SCS) is an effective non-drug treatment for chronic pain. Risks A psychological evaluation is required and not every patient is a candidate for SCS therapy. The stage 2 SCS implantation procedure is a minor surgery that does not require hospitalization. Patients will need a responsible adult and dependable transport home. Potential complication…

Read more Spinal column stimulation (SCS) for the treatment of chronic pain

Peripheral nerve stimulation (PNS) for chronic pain & post-surgical pain

“Peripheral nerve stimulation” (PNS) is a novel, effective, convenient, & minimally invasive non-drug treatment for chronic neuropathic pain & post-surgical pain. Benefits For single-nerve neuropathic pain, PNS lets the patient perform nerve treatments at home, for hours at a time, several times a day, while going about their usual activities. Many patients find over time…

Read more Peripheral nerve stimulation (PNS) for chronic pain & post-surgical pain

Lidocaine infusion

Lidocaine is a commonly used local anesthetic in medicine & dentistry. When infused directly into the blood, it can temporarily reduce all painsignals in the body. Pain physicians leverage this effect to reset chronic pain circuit. Benefits Lidocaine binds to voltage-gated sodium channels in the brain & nerves. By profoundly reducing pain signal, lidocaine infusion…

Read more Lidocaine infusion