CGRP plays a key role in central chronic pain by mediating “neurogenic inflammation”. In this process, sensory nerves which usually carry electrical signal from the body instead broadcast inflammatory signals into it. CGRP is the most important of the inflammatory signals. Treating CGRP can be helpful for chronic migraine & pain. Neurogenic inflammation Small sensory…
Headache medications taken too regularly can paradoxically cause a new headache, called medication overuse headache (MOH), that is constant, over & above the primary headache. The treatment is to stop the medications & treat the primary headache. Central sensitization Using rescue headache medications every day changes the balance of neurochemistry (in particular serotonin) in the…
Botox injections once every 3 months can help reduce migraine sufferers by reducing headache frequency & severity. The Protocol Botox is injected in small doses to at least 31 spots around the head & neck. Benefits Botox takes effect 1–2 weeks after injection, and lasts for 10–12 weeks. By profoundly reducing tone & tension in…
Sinus conditions can cause headaches and pressure pain in the forehead and around the nose. In patients with chronic migraines, sinus issues can be a frequent and severe trigger of migraine episodes. Sphenopalatine (SPG) Block The sinuses are difficult to target individually, but Pain physicians can hit the 1 nerve bundle sphenopalatine ganglion, a common way…
